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October 1, 2024
Ep -
37

The Cancer Vaccine: New Vaccines Could Stop Breast Cancer in Its Tracks with Kristen Dahlgren & Dr. Kiran Dhillon

In this episode of the SHE MD podcast, Kristen Dahlgren and Dr. Kiran Dhillon join us to discuss groundbreaking vaccines being developed to prevent and treat breast cancer. Did you know that one in eight women will be diagnosed with breast cancer in their lifetime? The first vaccines being developed are targeting the most aggressive forms of the disease, offering hope to those who need it now. Kristen and Dr. Dhillon share their involvement with the Cancer Vaccine Coalition and highlight the progress in targeting aggressive cancers such as ductal, lobular, and inflammatory breast cancers. They explain the challenges of funding these life-saving vaccines, the importance of early detection, and the role of personalized medicine. Tune in to learn about current clinical trials, how vaccines stop cancer recurrence, and how listeners can support this vital research. 

Visit the Cancer Vaccine Coalition website.

About the Guest

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Dr. Kiran Dhillon is the Executive Director of the UW Medicine Cancer Vaccine Institute. She received her PhD in Genetics from the University of Washington and then did her postdoctoral training at Fred Hutch where she studied why breast and ovarian cancer patients stop responding to chemotherapy. At the Cancer Vaccine Institute, she directs the overall strategic program goals, philanthropic relations, and overall administration to accelerate the development of therapeutic and preventative cancer vaccines for some of the most common and deadly cancers. Dr. Dhillon’s dedication to ending cancer is not just a professional pursuit but a personal one as she is a survivor of breast cancer herself. 

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Kristen Dahlgren  is an award winning journalist turned Breast Cancer advocate and founder of the nonprofit Cancer Vaccine Coalition.  For the first 30 years of her career, Kristen traveled the world, documenting some of the biggest news stories of our time.  She reported for NBC Nightly News and NBC's Today show, was nominated for an Emmy award for leading the network's coverage of the Parkland School shooting, served as a backup anchor for Lester Holt, and won an Edward R. Murrow award for her feature reporting.  In 2019, she was diagnosed with Breast Cancer and immediately decided to share her story to help other women to recognize the different ways their own cancers could present. Through her reporting, Kristen also learned about the research that was happening on Breast Cancer vaccines. After a conversation with UW Cancer Vaccine Institute's Dr. Nora Disis, Kristen realized that vaccines for breast cancer were no longer a "Pie in the sky" idea but something that was close and achievable. She couldn't stand by and watch anyone else suffer. CVC is partnered with the nation’s top vaccine and cancer researchers with a goal of getting a safe, effective breast cancer vaccine to market in 5 to 10 years.  CVC has one mission: to move science forward faster. To do so, CVC works to fund trials, streamline the process, remove barriers to success and ensure ALL breast cancer patients are represented in trials. 

Key Takeaways: 

  1. Schedule Regular Screenings: Encourage regular screenings for those you know. Breast cancer can affect anyone, regardless of family history.
  2. Support Cancer Vaccine Research: Donate to the Cancer Vaccine Coalition to help fund the development of life-saving breast cancer vaccines. The coalition does groundbreaking work in targeting aggressive breast cancers.
  3. Learn About Clinical Trials: If you or someone you know has breast cancer, explore current vaccine trials, especially if BRCA-positive. Kristen and Dr. Kiran discuss how listeners can get involved in these studies and help advance the development of vaccines.
  4. Stay Informed: Stay up to date on advancements in vaccines tailored to individual cancer profiles. This emerging field holds promise for treating cancers more effectively, and understanding your specific risks can lead to better treatment outcomes.
  5. Advocate for Increased Funding: Spread awareness about the need for more funding to make breast cancer vaccines widely available. Talk to your networks, share information from the episode, and encourage others to contribute to this critical cause.

In This Episode:

  • [00:00] Kristen and Dr. Dhillon explain how they got involved in the Cancer Vaccine Coalition.
  • [05:06] The different types of cancers and vaccines developed to target them; examples are ductal, lobular and inflammatory
  • [09:15] There are vaccines available; however, Kristen says there isn’t the funding needed and discussion of a study that started ten years ago and timelines for making the vaccines available to the public
  • [18:38] Kristen discusses barriers to working on vaccines, the composition of the Cancer Vaccine Coalition and personalized vaccines, and Dr. A tells about her journey with breast cancer
  • [25:28] Why younger women and men are getting cancer, how does the inflammation factor weigh in
  • [38:35] Vaccines and trials for BRCA-positive patients
  • [47:24] Dr. Dhillon explains how vaccines work, the current active studies and getting scientists together from all over the world to collaborate
  • [53:31] Results of the breast cancer study, expediting the studies and the number of clinical trials going on now and how much money it would take to completely fund those trials

Quotes:

“It was an easy pregnancy until it wasn't. I'm excited to be here with you today just because now that I have my child, I feel like people don't talk about all the things that go wrong after you give birth that are so hard. So, I'm excited to be here to talk to you about that and make people feel less alone.” Sofia Grainge

“With all my previous relationships, I found myself changing to be the right person for that person. And with Elliot, I knew he was the one because I could be 100% myself, and he loved it. He magnifies me as a person rather than trying to change me as a person. And same with him. We're such big personalities, both of us, and we both are each other's cheerleaders. There's nothing about each other we want to change. We're completely, and authentically ourselves.” Sofia Grainge

Resources:

Today Show - Kristen Dahlgren

Cancer Vaccine Coalition DONATE - Website

Clinical Trials - Gov

Cancer Vaccine Institute Trials- Website

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